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51.
Eugene Metakovsky Laura Pascual Patrizia Vaccino Viktor Melnik Marta Rodriguez-Quijano Yulia Popovych Sabina Chebotar William John Rogers 《International journal of molecular sciences》2021,22(4)
The Gli-B1-encoded γ-gliadins and non-coding γ-gliadin DNA sequences for 15 different alleles of common wheat have been compared using seven tests: electrophoretic mobility (EM) and molecular weight (MW) of the encoded major γ-gliadin, restriction fragment length polymorphism patterns (RFLPs) (three different markers), Gli-B1-γ-gliadin-pseudogene known SNP markers (Single nucleotide polymorphisms) and sequencing the pseudogene GAG56B. It was discovered that encoded γ-gliadins, with contrasting EM, had similar MWs. However, seven allelic variants (designated from I to VII) differed among them in the other six tests: I (alleles Gli-B1i, k, m, o), II (Gli-B1n, q, s), III (Gli-B1b), IV (Gli-B1e, f, g), V (Gli-B1h), VI (Gli-B1d) and VII (Gli-B1a). Allele Gli-B1c (variant VIII) was identical to the alleles from group IV in four of the tests. Some tests might show a fine difference between alleles belonging to the same variant. Our results attest in favor of the independent origin of at least seven variants at the Gli-B1 locus that might originate from deeply diverged genotypes of the donor(s) of the B genome in hexaploid wheat and therefore might be called “heteroallelic”. The donor’s particularities at the Gli-B1 locus might be conserved since that time and decisively contribute to the current high genetic diversity of common wheat. 相似文献
52.
53.
Jinchen Wei Lilai Jiang Menglin Huang Yuning Wu Shiyou Chen 《Advanced functional materials》2021,31(42):2104913
It is believed that promoting the fraction of ferroelectric orthorhombic phase (o-phase) through O-poor growth conditions can increase the spontaneous polarization of HfO2 and (Hf,Zr)O2 thin films. However, the first-principles calculations show that the growth may be limited by the easy formation of point defects in the orthorhombic and tetragonal phases of HfO2, ZrO2, and (Hf,Zr)O2. Their dominant defects, O interstitial (Oi) under O-rich conditions and O vacancy (VO) under O-poor condition, have low formation energies and quite high density (1016–1019 cm−3 for 800–1400 K growth temperature). Especially, Oi has negative formation energy in tetragonal HfO2 under O-rich condition, causing non-stoichiometry and limiting the crystalline-seed formation during o-phase growth. High-density defects can cause disordering of dipole moments and increase leakage current, both diminishing the polarization. These results explain the experimental puzzle that the measured polarization is much lower than the ideal value even in O-poor thin films and highlight that controlling defects is as important as promoting the o-phase fraction for enhancing ferroelectricity. The O-intermediate condition (average of O-rich and O-poor conditions) and low growth temperature are proposed for fabricating HfO2 and (Hf,Zr)O2 with fewer defects, lower leakage current, and stronger ferroelectricity, which challenges the belief that O-poor condition is optimal. 相似文献
54.
《Ceramics International》2022,48(11):15207-15217
SCAPS solar cell simulation program was applied to model an inverted structure of perovskite solar cells using Cu-doped Ni1-xO thin films as hole transport layer. The Cu-doped Ni1-xO film were made by co-sputtering deposition under different deposition conditions. By increasing the amount of the Cu-dopant, the film crystallinity enhanced whereas the bandgap energy decreased. The transmittance of the thin films decreased significantly by increasing the sputtering power of copper. High quality, uniform, compact, and pin-hole free films with low surface roughness were achieved. The structural, chemical, surface morphology, optical, electrical, and electronic properties of the Cu doped Ni1-xO films were used as input parameters in the simulation of Pb-based (MAPbI3-xClx) and Pb-free (MAGeI3) perovskite solar cells. Simulation results showed that the performance of both Pb-based and Pb-free perovskite solar cell devices significantly enhanced with Cu-doped Ni1-xO film. The highest power conversion efficiency (PCE) for the Pb-free perovskite solar cell is 8.9% which is lower than the highest PCE of 17.5% for the Pb-based perovskite solar cell. 相似文献
55.
An integrated model of ultrasonic vibration enhanced friction stir welding (UVeFSW) is developed by integrating the thermal-fluid model with the ultrasonic field model and tool torque model. The tool torque and the heat generation rate at tool/workpiece contact interfaces are coupled with the interfacial temperature, strain rate and ultrasonic energy density. The model is used in quantitatively analysing the effects of ultrasonic vibration on tool torque and thermal processes in friction stir welding (FSW). The results show that ultrasonic vibration reduces the flow stress, which results in a decreasing of tool torque, interfacial heat generation rate and interfacial temperature. The complicated interaction of ultrasonic energy with the thermal processes in FSW leads to a gentle thermal gradient and an enhanced plastic material flow in UVeFSW. The model is validated by a comparison of the calculated thermal cycles and tool torque at various welding parameters with the experimentally measured ones. 相似文献
56.
在全国天然气管道“主干互联、区域成网”(以下简称“互联互通”)基础格局逐渐形成的背景下,天然气管网规模日益扩大、管道分支和气源增加,并且分布不集中、输送方向可变,使得输气方案更加灵活,可以更好地解决某些地域的供气紧张问题;但受现有站场和设备的限制,暂不能满足某些多线组合极限工况,使得“互联互通”的初衷难以全部实现。为了使得现有的各输气干线在实现“互联互通”之后可以满足更多的多线组合工况,在分析“互联互通”背景下M管网工况变化的基础上,研发了可以进行水力仿真和压气站方案制订的计算软件,并对3种极限工况下的不同输气量情况进行了可行性试算,进而基于试算结果提出了相应的管网改进建议。研究结果表明:(1)经验证,软件计算误差满足要求;(2)在M管道某处增设压气站或在某些输气站场配置压缩机组;(3) M管网改进调整后,可以完成大部分的多线组合极限工况,真正实现“互联互通”的输气方案。结论认为,该研究成果有助于推进全国天然气管网早日实现“互联互通”。 相似文献
57.
Marta Gabasa Marselina Arshakyan Alejandro Llorente Lourdes Chuli-Peris Irina Pavelescu Antoni Xaubet Javier Pereda Jordi Alcaraz 《International journal of molecular sciences》2020,21(22)
Pro-inflammatory cytokines like interleukin-1β (IL-1β) are upregulated during early responses to tissue damage and are expected to transiently compromise the mechanical microenvironment. Fibroblasts are key regulators of tissue mechanics in the lungs and other organs. However, the effects of IL-1β on fibroblast mechanics and functions remain unclear. Here we treated human pulmonary fibroblasts from control donors with IL-1β and used Atomic Force Microscopy to unveil that IL-1β significantly reduces the stiffness of fibroblasts concomitantly with a downregulation of filamentous actin (F-actin) and alpha-smooth muscle (α-SMA). Likewise, COL1A1 mRNA was reduced, whereas that of collagenases MMP1 and MMP2 were upregulated, favoring a reduction of type-I collagen. These mechanobiology changes were functionally associated with reduced proliferation and enhanced migration upon IL-1β stimulation, which could facilitate lung repair by drawing fibroblasts to sites of tissue damage. Our observations reveal that IL-1β may reduce local tissue rigidity by acting both intracellularly and extracellularly through the downregulation of fibroblast contractility and type I collagen deposition, respectively. These IL-1β-dependent mechanical effects may enhance lung repair further by locally increasing pulmonary tissue compliance to preserve normal lung distension and function. Moreover, our results support that IL-1β provides innate anti-fibrotic protection that may be relevant during the early stages of lung repair. 相似文献
58.
59.
在当前Web服务海量增加、现有Web服务选择算法低效、用户匹配度差的基础上,针对K中心点算法存在的质点偏移、准确率低和容易发生畸变等问题,提出一种大数据环境下基于K中心点优化算法的Web服务组合方法。该方法是在大数据环境下,根据不同用户需求满意度及Web服务QoS参数,对基于优化初始聚类中心的K中心点算法的Web服务选择及最优Web服务组合进行研究。同时针对不同的选择方法对服务动态选择及组合的准确度、迭代更新次数、候选集选择时间及选择总时间进行实验分析,验证了本文研究方法的有效性和可靠性。 相似文献
60.
针对连续查询位置服务中构造匿名区域未考虑语义位置信息导致敏感隐私泄露问题,通过设计[(K,θ)]-隐私模型,提出一种路网环境下面向连续查询的敏感语义位置隐私保护方案。该方案利用Voronoi图将城市路网预先划分为独立的Voronoi单元,依据用户的移动路径和移动速度,选择具有相似特性的其他[K-1]个用户,构建匿名用户集;利用匿名用户集用户设定的敏感语义位置类型和语义安全阈值,以及用户所处语义位置的Voronoi单元,构建满足[(K,θ)]-隐私模型的语义安全匿名区域,可以同时防止连续查询追踪攻击和语义推断攻击。实验结果表明,与SCPA算法相比,该方案在隐私保护程度上提升约15%,系统开销上降低约20%。 相似文献